Publications

82. 覃凌云, 聂泽锋, 唐淳. (2021 泛素链的体外制备、磷酸化修饰与标记方法. 生物化学与生物物理进展

81. Czaplewski C, Gong Z, Lubecka EA, Xue K, Tang C, Liwo A. (2021) Recent Developments in Data-Assisted Modeling of Flexible Proteins.  Front. Mol. Biosci, doi.org/10.3389/fmolb.2021.765562

80. Fu WT, Zhang MK, Liao JN, Tang Q, Lei YX, Gong Z, Shan LH, Duan MJ, Chai X, Pang JP, Tang C, Wang XW, Xu XH, Li D, Sheng R, Hou TJ.  (2021)  Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers. J. Med. Chemdoi.org/10.1021/acs.jmedchem.1c01287

79. 陈聪, 易华伟, 沈晨, 高童谣, 唐淳, 张纬萍. (2021) sPINK1抑制泛素依赖蛋白酶体的活性损伤神经元. 中国药理学与毒理学杂志, 35(09):652 

78. Kogut M, Gong Z, Tang C, Liwo A. (2021)Pseudopotentials for coarse-grained cross-link-assisted modeling of protein structures. J Comput Chem42 (29) : 2054-2067

77. 张志武, 杨菊, 聂泽锋, 叶尚祥, 董旭, 唐淳. (2021) 基于19F化学标记磷酸化泛素的温度传感器开发. 19F化学标记磷酸化泛素的温度传感器开发%20http://121.43.60.238/bpxzz/CN/10.11938/cjmr20202867">波谱学杂志,, 38(02):173-181

76. Qin LY, Gong Z, Liu K, Dong X and Tang C. (2021)Kinetic Constraints in the Specific Interaction between Phosphorylated Ubiquitin and Proteasomal Shuttle FactorsBiomolecules,10.3390 / biom11071008 

75.  Lerner E, Barth A, Hendrix J, Ambrose B, Birkedal V, Blanchard SC, Börner R, Chung HS, Cordes T, Craggs TD, Deniz AA, Diao JJ, Fei JY, Gonzalez RL, Gopich IV, Ha T, Hanke CA, Haran G, Hatzakis NS, Hohng SC, Hong SC, Hugel T, Ingargiola A, Joo C, Kapanidis AN, Kim HD, Laurence T, Lee NK, Lee TH, Lemke EA, Margeat E, Michaelis J, Michalet X, Myong S, Nettels D, Peulen TO, Ploetz E, Razvag Y, Robb NC, Schuler B, Soleimaninejad H, Tang C, Vafabakhsh R, Lamb DC, Seidel CA, Weiss S.  (2021) FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices. eLife, 2021;10:e60416

74. Gong Z, Ye SX and Tang C. (2020) Tightening the Crosslinking Distance Restraints for Better Resolution of Protein Structure and Dynamics. Structure, 28:1160-1167

73. Yang J, Gong Z, Lu YB, Xu CJ, Wei TF, Yang MS, Zhan TW, Yang YH, Lin L, Liu JF, Tang C and Zhang WP. (2020) FLIM–FRET-Based Structural Characterization of a Class-A GPCR Dimer in the Cell Membrane. J Mol Biol,432:4596-4611

72. Gong Z, Yang S, Dong X, Yang QF, Zhu YL, Xiao Y, Tang C. (2020)Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches.  J Mol Biol 4 32:4523-4543 

71. Gong Z, Ye SX, Nie ZF and Tang C. (2020) The Conformational Preference of Chemical Cross-linkers Determines the Cross-linking Probability of Reactive Protein Residues.  J Phy Chem B , 123:4446-4453

70. Tang C , Gong Z. (2020) Integrating Non-NMR Distance Restraints to Augment NMR Depiction of Protein Structure and Dynamics. J Mol Biol,432:2913-2929

69. Tang C and Zhang wp. (2020)  How Phosphorylation by PINK1 Remodels the Ubiquitin System: A Perspective from Structure and Dynamics. Biochemistry, 59:26-33

68. You ZY, Jiang WX, Qin LY, Gong Z, Wan W, Li J, Wang YS, Zhang HT, Peng C, Zhou TH, Tang C and Liu W. (2019) Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stressNat Commun,10:5792

67. Gong Z, Yang S, Yang QF, Zhu YL, Jiang J and Tang C. (2019) Refining RNA solution structures with the integrative use of label-free paramagnetic relaxation enhancement NMR. Biophys. Rep, 5:244-253

66. Ye SX, Gong Z, Yang J, An YX, Liu Z, Zhao Q, Lescop E, Dong X, Tang C. (2019) Ubiquitin is double-phosphorylated by PINK1 for enhanced pH-sensitivity of conformational switch. Protein & Cell,  10:908-913

65. Yang QF, Tang C. (2019) On the necessity of an integrative approach to understand protein structural dynamics. J Zhejiang Univ Sci B, 20(6):496-502

64. Liu Z, Dong X, Yi HW, Yang J, Gong Z, Wang Y, Liu K, Zhang WP, Tang C. (2019) Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13. Cell Discov, 5:19

63. 冉梦琳, 覃凌云, 唐淳, 董旭. (2019) 磷酸化调控泛素单体与Rad23A/Ubiquilin-1中泛素结合域互作的检测. 波谱学杂志, 36(01):15-22

62. Huang JB, Dong X, Gong Z, Qin LY, Yang S, Zhu YL, Wang X, Zhang DL, Zou TT, Yin P and Tang C. (2019) Solution structure of the RNA recgonition domain of METTL3-METTL14 N6-methyladenosine methyltransferase. Protein & Cell, 10:272-284

61. Yang QF, Tang C. (2019) On the necessity of an integrative approach to understand protein structural dynamics. J ZHEJIANG UNIV-SC B, 20:496–502

60. 杨菊, 龚州, 吴明, 魏尔清, 卢韵碧, 唐淳, 张纬萍. (2018) GPR17同源二聚体结构与功能的研究. 中国药理学与毒理学杂志, 32(09):739

59. Gong Z, Charles DS and Tang C. (2018) Theory and practice of using solvent paramagnetic relaxtion enhancement to characterize protein conformational dynamics. Methods, 148:48-56

58. Zhang XY, Wang JH, Tan D, Li Q, Li MD, Gong Z, Tang C, Liu ZL, Dong MQ, Lei XG. (2018). Carboxylate-selective chemical cross-linkers for mass spectrometric analysis of protein structures. Anal Chem, 90: 1195-1201

57. Liu Z, Gong Z, Cao Y, Ding YH, Dong MQ, Lu YB, Zhang WP, Tang C. (2018). Characterizing Protein Dynamics with Integrative Use of Bulk and Single-Molecule Techniques. Biochemistry, 57:305-313

56. Gong Z, Liu Z, Dong X, Ding YH, Dong MQ, Tang C. (2017). Protocol for analyzing protein ensemble structures from chemical cross-links using DynaXL. Biophys. Rep. 3, 100-108

55. Dong X, Gong Z, Lu YB, Liu K, Qing LY, Ran ML, Zhang CL, Liu Z, Zhang WP, Tang C. (2017). Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch. Proc Natl Acad Sci, USA114:6770-6775

54. Ge Fang, Binquan Luan, Cuicui Ge, Yu Chong, Xu Dong, Jun Guo, Chun Tang, Ruhong Zhou. (2017). Understanding the graphene quantum dots-ubiquitin interaction by identifying the interaction sites. Carbon112:285-291

53. Jiang WX, Gu XH,Dong X, Tang C. (2017). Lanthanoid tagging via an unnatural amino acid for protein structure characterization. J Biomol NMR,67:273-282

52. Guo XD, Yan CS, Li H, Huang WM, Shi XS, Huang M, Yang YF, Pan WL, Cai MJ, Li LY, Wu W, Bai YB, Zhang C, Liu ZJ, Wang XY, Zhang XH, Tang C, Wang HD, Liu WL, Wong CC, Cao Y, Xu CQ. (2017). Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor. Cell Research, 27,505-525

51. Ding YH, Gong Z, Dong X, Liu K, Liu Z, Liu C, He SM, Dong MQ, Tang C. (2017). Modeling protein excited-state structures from "over-length" chemical cross-links. J Biol Chem292,1187-1196

50. Gong Z, Gu XH, Guo DC, Wang J, Tang C. (2017). Protein structural ensembles visualized by solvent paramagnetic relaxation enhancement. Angew Chem Int Ed, 56,1002-1006

49. Zhang JR, Liu N, Chacho RA, Gong Z, Liu Z, Qin WM, Tang C, Tang Y, Zhou JH. (2016).  Structural basis of nonribosomal pepetide macrocyclization in fungi. Nat Chem Biol12, 1001-1003

48. Wang X, Feng J, Xue Y, Guan ZY, Zhang DL, Liu Z, Gong Z, Wang Q, Huang JB, Tang C, Zou TT, Yin P. (2016) Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex. Nature, 534,575-578.

47. Fang J, Cheng J, Wang J, Zhang Q, Liu M, Gong R, Wang P, Zhang X, Feng Y, Lan W, Gong Z, Tang C, Wong J, Yang H, Cao C, Xu Y. (2016) Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition. Nature Communications, doi:10.1038/ncomms11197.

46. Jiang WX, Dong X, Jiang J, Yang YH, Yang J, Lu Yb, Fang SH, Wei EQ, Tang C, and Zhang WP. (2016) Specific cell surface labeling of GPCRs using split GFP. Sci.Rep. 6:20568

45. Liu Z and Tang C. (2016) Ensemble structure description of Lys63-linked diubiquitin. Data in Brief, doi:10.1016/j.dib.2016.02.003.

44. 阳雨虹, 唐淳 ,顾新华. (2016) 蛋白质定点标记的近红外荧光探针的合成研究. 化学通报, 79(09):856-859,875

43. 陈少敏, 唐淳 ,龚洲. (2016) 铽离子-镧系金属结合标签的荧光探针的改进. 波谱学杂志,, 33(01):106-116

42. Liu Z, Gong Z, Dong X and Tang C. (2016) Transient protein-protein interactions visualized by solution NMR. BBA Proteins and Proteomics, 1864, 115-122[pubmed] 

41. Gong Z, Ding YH, Dong X, Liu N, Zhang EE, Dong MQ and Tang C. (2015) Visualizing the ensemble structures of protein complexes using chemical cross-linking coupled with mass spectrometry. Biophys.Rep., 1, 127-138

40. 刘主, 龚洲, 唐淳. (2015) 泛素蛋白及其多聚体动态结构和功能的研究. 中国科学基金, 29(06):457-460

39. Liu Z, Gong Z, Jiang WX, Yang J, Zhu WK, Guo DC, Zhang WP, Liu ML and Tang C. (2015) Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition. eLife,4:e05767[pubmed]

38. Zhang XQ, Lu JT, Jiang WX, Lu YB, Wu M, Wei EQ, Zhang WP and Tang C. (2015) NAMPT inhibitor and metabolite protect mouse brain from cryoinjury through distinct mechanisms. Neuroscience, 291, 230-40[pubmed]

37. Gong Z, Charles DS and Tang C. (2015) Conjoined use of EM and NMR in RNA structure refinement. Plos One, 10, e0120445[pubmed]

36. Xing Q, Huang P, Yang J, Sun JQ, Gong Z, Dong X, Guo DC, Chen SM, Yang YH, Wang Y, Yang MH, Yi M, Ding YM, Liu ML, Zhang WP and Tang C. (2014) Visualizing an ultra-weak protein-protein interaction in phosphorylation signaling. Angew Chem Int Ed ,53, 11501-11505[pubmed] (back cover)

35. Wang Y, Tang C, Wang EK and Wang J. (2014) Polyubiquitin chain linkage topology selects the functions from the underlying binding landscape. Plos Comput Biol10[pubmed]

34. Zhang Z, Zhang TL, Wang SS, Gong Z, Tang C, Chen JY and Ding JP. (2014) Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5. eLife, doi:10.7554/eLife.02687[pubmed]

33. Rathinavelan T, Lara-Tejero M, Lefebre M, Chatterjee S, McShan AC, Guo DC, Tang C, Galan JE and De Guzman RN. (2014) NMR model of prgI-sipD interaction and its implications in the needle-tip assembly of the salmonella type III secretion system. J Mol Biol 426, 2958-2969. [pubmed]

32. Liu Z, Gong Z, Guo DC, Zhang WP and Tang C. (2014) Subtle dynamics of holo glutamine binding protein revealed with a rigid paramagnetic probe. Biochemistry-Us, 53, 1403-1409. [pubmed]

31. Gu XH, Gong Z, Guo DC, Zhang WP and Tang C. (2014) A decadentate Gd(III)-coordinating paramagnetic cosolvent for protein relaxation enhancement measurement. J Biomol NMR, 58, 149-154. [pubmed]

30. Coffman K, Yang B, Lu J, Tetlow AL, Pelliccio E, Lu S, Guo DC, Tang C, Dong MQ and Tamanoi F. (2014) Characterization of the Raptor/ 4E-BP1 Interaction by chemical cross- linking coupled with mass spectrometry analysis. J Biol Chem, 289, 4723-4734. [pubmed]

29. Zhao B, Zhang M, Han X, Zhang XY, Xing Q, Dong X, Shi QJ, Huang P, Lu YB, Wei EQ, Xia Q, Zhang WP and Tang C. (2013) Cerebral ischemia is exacerbated by extracellular nicotinamide phosphoribosyltransferase via a non-enzymatic mechanism. Plos One, 8. [pubmed]

28. Li CG, Tang C and Liu ML. (2013) Protein dynamics elucidated by NMR technique. Protein Cell, 4, 726-730. [pubmed]

27. Jiang B, Luo F, Ding YM, Sun P, Zhang X, Jiang L, Li CG, Mao XA, Yang DW, Tang C and Liu ML. (2013) NASR: an effective approach for simultaneous noise and artifact suppression in NMR spectroscopy. Anal Chem, 85, 2523-2528. [pubmed]

26. Wang Y, Tang C, Wang EK and Wang J. (2012) Exploration of multi-state conformational dynamics and underlying global functional landscape of maltose binding protein. Plos Comput Biol,8. [pubmed]

25. Liu Z, Zhang WP, Xing Q, Ren XF, Liu ML and Tang C. (2012) Noncovalent dimerization of ubiquitin. Angew Chem Int Ed, 51, 469-472. [pubmed]

24. 刘主,唐淳. (2011) 顺磁弛豫增强技术与蛋白质瞬态结构. 波谱学杂志, 28, 301-316.

23. Rathinavelan T, Tang C and De Guzman RN. (2011) Characterization of the interaction between the salmonella type III secretion system tip protein sipD and the needle protein prgI by paramagnetic relaxation enhancement. J Biol Chem, 286, 4922-4930. [pubmed]

22. Yu DM, Volkov AN and Tang C. (2009) Characterizing dynamic protein-protein interactions using differentially scaled paramagnetic relaxation enhancement. J Am Chem Soc, 131, 17291-17297. [pubmed]

Before 2009

21. Tang C, Louis JM, Aniana A, Suh JY and Clore GM. (2008) Visualizing transient events in amino-terminal autoprocessing of HIV-1 protease. Nature, 455, 693-696. [pubmed]

20. Tang C, Ghirlando R and Clore GM. (2008) Visualization of transient ultra-weak protein self-association in solution using paramagnetic relaxation enhancement. J Am Chem Soc, 130, 4048-4056. [pubmed]

19. Kim YC, Tang C, Clore GM and Hummer G. (2008) Replica exchange simulations of transient encounter complexes in protein-protein association. P Natl Acad Sci USA, 105, 12855-12860. [pubmed]

18. Tang C, Schwieters CD and Clore GM. (2007) Open-to-closed transition in apo maltose-binding protein observed by paramagnetic NMR. Nature 449, 1078-1082. [pubmed]

17. Clore GM, Tang C and Iwahara J. (2007) Elucidating transient macromolecular interactions using paramagnetic relaxation enhancement. Curr Opin Struc Biol, 17, 603-616. [pubmed]

16. Iwahara J, Tang C and Marius Clore G. (2007) Practical aspects of (1)H transverse paramagnetic relaxation enhancement measurements on macromolecules. Journal of magnetic resonance, 184, 185-195. [pubmed]

15. Kelly BN, Kyere S, Kinde I, Tang C, Howard BR, Robinson H, Sundquist WI, Summers MF and Hill CP. (2007) Structure of the antiviral assembly inhibitor CAP-1 complex with the HIV-1 CA protein. J Mol Biol, 373, 355-366. [pubmed]

14. Suh JY, Tang C and Clore GM. (2007) Role of electrostatic interactions in transient encounter complexes in protein-protein association investigated by paramagnetic relaxation enhancement. J Am Chem Soc, 129, 12954-12955. [pubmed]

13. Tang C, Iwahara J and Clore GM. (2006) Visualization of transient encounter complexes in protein-protein association. Nature, 444, 383-386. [pubmed]

12. Tang C and Clore GM. (2006) A simple and reliable approach to docking protein-protein complexes from very sparse NOE-derived intermolecular distance restraints. J Biomol NMR, 36, 37-44. [pubmed]

11. Tang C, Williams DC, Ghirlando R and Clore GM. (2005) Solution structure of enzyme IIA(Chitobiose) from the N,N '-diacetylchitobiose branch of the Escherichia coli phosphotransferase system. J Biol Chem 280, 11770-11780. [pubmed]

10. Suh JY, Tang C, Cai ML and Clore GM. (2005) Visualization of the phosphorylated active site loop of the cytoplasmic B domain of the mannitol transporter IIMannitol of the Escherichia coli phosphotransferase system by NMR spectroscopy and residual dipolar couplings. J Mol Biol 353, 1129-1136. [pubmed]

9. Tang C, Iwahara J and Clore G. (2005) Accurate determination of leucine and valine side-chain conformations using U-[N-15/C-13/H-2]/[H-1-(methine/methyl)-Leu/Val] isotope labeling, NOE pattern recognition, and methine C gamma-H gamma/C beta-H beta residual dipolar couplings: application to the 34-kDa enzyme IIA (Chitobiose). J Biomol NMR 33, 105-121. [pubmed]

8. Tang C, Loeliger E, Luncsford P, Kinde I, Beckett, D and Summers MF. (2004) Entropic switch regulates myristate exposure in the HIV-1 matrix protein. P Natl Acad Sci USA 101, 517-522. [pubmed]

7. Tang C, Loeliger E, Kinde I, Kyere S, Mayo K, Barklis E, Sun YN, Huang MJ and Summers MF. (2003) Antiviral inhibition of the HIV-1 capsid protein. J Mol Biol 327, 1013-1020. [pubmed]

6. Gatanaga H, Suzuki Y, Tsang H, Yoshimura K, Kavlick MF, Nagashima K, Gorelick R. J, Mardy S, Tang C, Summers MF and Mitsuya H. (2002) Amino acid substitutions in Gag protein at non-cleavage sites are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors. J Biol Chem 277, 5952-5961. [pubmed]

5. Tang C, Ndassa Y and Summers MF. (2002) Structure of the N-terminal 283-residue fragment of the immature HIV-1 Gag polyprotein. Nat Struct Biol 9, 537-543. [pubmed]

4. Lin J, Blake M, Tang C, Zimmer D, Rustandi RR, Weber DJ and Carrier F. (2001) Inhibition of p53 transcriptional activity by the S100B calcium-binding protein. J Biol Chem, 276, 35037-35041. [pubmed]

3. Gu T, Tang C and Xu ZD. (1999) Synthesis of C-60 nitroxide derivatives. Chinese Chem Lett, 10,95-96.

2. Gu T, Tang, C and Xu ZD. (1999) Two methods to synthesize C-60 nitroxide derivatives. Fullerence Sci Techn, 7,297-303.

1. Baldisseri DM, Rustandi RR, Zhang ZS, Tang C, Bair C. L, Landar A, Landar A, Zimmer DB and Weber DJ。(1999) Inhibition of p53 Transcriptional Activity by the S100B Calcium-binding Protein*. J Biomol NMR,  14,91-92  。 [发表]